Impact of tumor location on resectability and survival for pancreatic ductal adenocarcinoma
نویسندگان
چکیده
منابع مشابه
The prognostic influence of intrapancreatic tumor location on survival after resection of pancreatic ductal adenocarcinoma
BACKGROUND The prognosis of pancreatic ductal adenocarcinoma (PDAC) is worse when the tumor is located in the pancreatic body or tail, compared to being located in the pancreatic head. However, for localized, resectable tumors survival seems to be at least similar. METHODS We analyzed and compared the outcome after pancreatoduodenectomy (PD) and distal pancreatectomy (DP) for PDAC at our inst...
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Tumor-stroma interactions in pancreatic ductal adenocarcinoma.
The host stromal response to an invasive epithelial carcinoma is frequently called a desmoplastic reaction (DR) and is a universal feature of pancreatic ductal adenocarcinoma (PDA). This DR is characterized by a complex interplay between the normal host epithelial cells, invading tumor cells, stromal fibroblasts, inflammatory cells, proliferating endothelial cells, an altered extracellular matr...
متن کاملThe prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma
Different clinical presentations and prognoses have been implied between pancreatic head and body/tail cancers. We aimed to identify the prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma (PDAC). Thirty-two pairs of patients with strictly matched early stage (II) pancreatic head and body/tail cancers were enrolled. The molecular ...
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Early diagnosis and treatment in pancreatic ductal adenocarcinoma (PDAC) is still a challenge worldwide. The poor survival of PDAC patients mainly due to early metastasis when first diagnosed and lack of prognostic biomarker. Ribosomal protein L15 (RPL15), an RNA-binding protein, is a component of ribosomal 60S subunit. It was reported that RPL15 is dysregulated in various type of cancers. Howe...
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ژورنال
عنوان ژورنال: HPB
سال: 2018
ISSN: 1365-182X
DOI: 10.1016/j.hpb.2018.02.238